Notes (required for cases diagnosed 1/1/2024 & forward)          

Note 1: This SSDI is effective for diagnosis years 2024+

  • For cases diagnosed 2018-2023, leave this SSDI blank

Note 2: Code 0 for p16 expression of weak intensity or limited distribution.

Note 3: This data item must be based on testing results for p16 overexpression.

  • Testing for HPV by DNA, mRNA, antibody, or other methods should not be coded in this data item
  • Do not confuse p16 with HPV, which is a specific strain of virus. A statement of a patient being HPV positive or negative is not enough to code this data item.

    p16Description
    0

    p16 Negative; Nonreactive

    1

    p16 Positive; Diffuse, Strong reactivity

    8

    Not applicable: Information not collected for this case
    (If this time is required by your standard setter, use of code 8 will result in an edit error)

    9

    Not tested for p16; Unknown

    <BLANK>

    N/A - Diagnosis year is prior to 2023


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