Organization |
Field Name |
ID |
Required |
---|---|---|---|
KCR |
Grade Post Therapy Clin (yc) |
30141 |
yes |
SEER |
Grade Post Therapy Clin (yc) |
1068 |
yes |
Note 1 Leave Grade Post Therapy Clin (yc) blank when
- No neoadjuvant therapy
- Clinical or pathological case only
- Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor
- There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological
Note 2 Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy.
Note 3 If there are multiple tumors with different grades abstracted as one primary, code the highest grade.
Note 4 Codes L and H take priority over A-D.
Note 5 Code 9 (unknown) when
- Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented
- Microscopic exam is done after neoadjuvant therapy and there is no residual cancer
- Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available
Code |
Description |
---|---|
L |
LG: Low grade: round monomorphic nuclei with only mild to moderate nuclear size variation, indistinct nucleoli, and chromatin characteristics resembling those of normal parathyroid or of adenoma |
H |
HG: High grade: more pleomorphism, with a nuclear size variation greater than 4:1; prominent nuclear membrane irregularities; chromatin alterations, including hyperchromasia or margination of chromatin; and prominent nucleoli. High-grade tumors show several discrete confluent areas with nuclear changes |
A |
Well differentiated |
B |
Moderately differentiated |
C |
Poorly differentiated |
D |
Undifferentiated, anaplastic |
9 |
Grade cannot be assessed (GX); Unknown |
<BLANK> |
See Note 1 |