Organization

Field Name

ID

Required

KCR

Grade Post Therapy Clin (yc)

30141

yes 

SEER

Grade Post Therapy Clin (yc)

1068

yes 

Note 1 Leave Grade Post Therapy Clin (yc) blank when

  • No neoadjuvant therapy
  • Clinical or pathological case only
  • Neoadjuvant therapy completed, no microscopic exam is done prior to surgery/resection of primary tumor
  • There is only one grade available and it cannot be determined if it is clinical, pathological, post therapy clinical or post therapy pathological

Note 2 Assign the highest grade from the microscopically sampled specimen of the primary site following neoadjuvant therapy or primary systemic/radiation therapy.

Note 3 If there are multiple tumors with different grades abstracted as one primary, code the highest grade.

Note 4 Codes 1-4 take priority over codes A-D.

Note 5 Code 9 (unknown) when

  • Microscopic exam is done after neoadjuvant therapy and grade from the primary site is not documented
  • Microscopic exam is done after neoadjuvant therapy and there is no residual cancer
  • Grade checked “not applicable” on CAP Protocol (if available) and no other grade information is available

Code

Description

1

G1: Nucleoli absent or inconspicuous and basophilic at 400x magnification
Stated as WHO/ISUP Grade 1

2

G2: Nucleoli conspicuous and eosinophilic at 400x magnification, visible but not prominent at 100x magnification
Stated as WHO/ISUP Grade 2

3

G3: Nucleoli conspicuous and eosinophilic at 100x magnification
Stated as WHO/ISUP Grade 3

4

G4: Marked nuclear pleomorphism and/or multinucleate giant cells and/or rhabdoid and/or sarcomatoid differentiation
Stated as WHO/ISUP Grade 4

A

Well differentiated

B

Moderately differentiated

C

Poorly differentiated

D

Undifferentiated, anaplastic

9

Grade cannot be assessed (GX); Unknown
Only Fuhrman grade documented

<BLANK>

See Note 1