Organization

Field Name

ID

Required

KCR

Multigene Signature Results

34092

yes 

SEER

Multigene Signature Result

3895

yes 

Note 1 Physician statement of the Multigene Signature Results can be used to code this data item.

Note 2 Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis.

  • Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA)

Note 3 Code the score or risk for the test performed. The same test should be used to record information in Multigene Signature Method (NAACCR Data Item #3894).

Note 4 Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx.

  • Oncotype Dx Recurrence Score-DCIS (NAACCR Data Item #3903)
  • Oncotype Dx Recurrence Score-Invasive (NAACCR Data Item #3904)
  • Oncotype Dx Risk Level-DCIS (NAACCR Data Item #3905)
  • Oncotype Dx Risk Level-Invasive (NAACCR Data Item #3906)

Note 5 PAM50 (Prosigna) is a single numeric score of 0-100. If the score is available, record the score. If only the risk level is available, record that.

Note 6 For Mammaprint, EndoPredict, and Breast Cancer Index, only record the risk level.

Code

Description

00-99

Enter actual recurrence score
Note: Depending on the test, the range of values may be different

X1

Score 100

X2

Low risk

X3

Moderate (intermediate) risk

X4

High risk

X7

Test done, results not in chart

X8

Not applicable: Information not collected for this case
(If this item is required by your standard setter, use of code X8 will result in an edit error.)

X9

Not documented in medical record
Multigene Signature Results not assessed or unknown if assessed