Organization

Field Name

ID

Required

KCR

Multigene Signature Method

34091

yes 

SEER

Multigene Signature Method

3894

yes 

Note 1 Physician statement of the Multigene Signature Method can be used to code this data item.

Note 2 Multigene signatures or classifiers are assays of a panel of genes from a tumor specimen, intended to provide a quantitative assessment of the likelihood of response to chemotherapy and to evaluate prognosis or the likelihood of future metastasis.

  • Only record tests done on tumor tissue that help determine if the cancer is likely to recur. Don’t include other tests, such as those that evaluate hereditary mutations that influence a patient’s risk of developing cancer (e.g. myRisk, BRCA)

Note 3 Code the type of test performed. The same test should be used to record information in Multigene Signature Results (NAACCR Data Item #3895).

Note 4 Oncotype Dx tests are not recorded in this data item. See the following data items for Oncotype Dx.

  • Oncotype Dx Recurrence Score-DCIS (NAACCR Data Item #3903)
  • Oncotype Dx Recurrence Score-Invasive (NAACCR Data Item #3904)
  • Oncotype Dx Risk Level-DCIS (NAACCR Data Item #3905)
  • Oncotype Dx Risk Level-Invasive (NAACCR Data Item #3906)

Code

Description

1

Mammaprint

2

PAM50 (Prosigna)

3

Breast Cancer Index

4

EndoPredict

5

Test performed, type of test unknown

6

Multiple tests, any tests in codes 1-4

7

Test ordered, results not in chart

8

Not applicable: Information not collected for this case
(If this item is required by your standard setter, use of code 8 will result in an edit error.)

9

Not documented in medical record
Multigene Signature Method not assessed or unknown if assessed