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Effective with diagnoses in 2005 and later, use the SEER Rx program (available from web site: http://seer.cancer.gov/tools/seerrx/) to identify immunotherapeutic agents. For pre-2005 cases, refer to Appendix H and to the Self-Instructional Manual for Tumor Registrars: Book 8 - Antineoplastic Drugs, Third Edition.