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  • Tumor involvement or treatment may destroy hormone-producing tissue. Hormone replacement therapy will be given if the hormone is necessary to maintain normal metabolism and body function. Do not code hormone replacement therapy as part of first course therapy, except for thyroid replacement therapy, as described above.

  • Use the SEER Rx program (available from web site: http://seer.cancer.gov/tools/seerrx/) to identify hormonal agents.  For pre-2005 diagnoses, refer to Appendix H and to the Self-Instructional Manual for Tumor Registrars: Book 8 - Antineoplastic Drugs, Third Edition.

  • Code surgery or radiation given for hormonal effect under Transplant/Endocrine Procedures (Item # 50220).