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11. Multifocal/multicentric tumors: Code the size of the largest invasive tumor, or the largest in situ tumor if all tumors are in situ, when the tumor is multi-focal or when multiple tumors are reported as a single primary.

12. Assign code 000 when

a. No residual tumor is found

i. Neoadjuvant therapy has been administered and the resection shows no residual

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tumor

b. Schema is Cervical Lymph Nodes and Unknown Primary 00060

c. EOD Primary Tumor is coded 800 (No evidence of primary tumor) for any schema

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except for those listed in Coding Instruction 14

13. Assign tumor size for benign and borderline tumors in the schemas Brain, CNS Other, Intracranial Gland, and Medulloblastoma when provided; do not default to 999

14. Assign code 999 when

a. Size is unknown and for the following sites and schemas/schema IDs

i. Any case coded to primary site C420, C421, C423, C424, C770-C779, or C809

ii. HemeRetic 00830

1. Excluding Spleen (C422)

iii. Kaposi Sarcoma 00458

iv. Lymphoma 00790

v. Lymphoma-CLL/SLL 00795

vi. Melanoma Choroid and Ciliary Body 00672

vii. Melanoma Iris 00671

viii. Plasma Cell Disorders 00822

ix. Plasma Cell Myeloma 00821

b. The only measurement describes pieces or chips in a pathology report. Do not add the

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size of pieces or chips together to create a whole; they may not be from the same

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location, or they may represent only a very small portion of a large tumor.

However, when the pathologist states an aggregate or composite size (determined by

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fitting the tumor pieces together and measuring the total size), record that size.

c. The only measurement is for calcifications that span given distance or a cluster of

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microcalcifications. Do not record the size of calcifications as tumor size. If there is no

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measurement of the mass or tumor, record 999.

d. Neoadjuvant therapy has been administered and resection was performed. Do not use a

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post-neoadjuvant size to code pathologic tumor size; however, you may use the clinical

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tumor size if available.

15. Document the information to support coded tumor size in the appropriate text data item of the abstract Tumor size is important for staging of tumors in the following table of schemas. For more information about schemas and schema IDs, go to the SSDI Manual, Appendix A.

Table. Schemas for which Tumor Size Affects Staging