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Code

Label

Description

0

Benign

(Reportable for intracranial and CNS sites only)

Benign

1

Borderline

(Reportable for intracranial and CNS sites only)

Uncertain whether benign or malignant

Borderline malignancy

Low malignant potential

Uncertain malignant potential

2

In situ and/or carcinoma in situ

Adenocarcinoma in an adenomatous polyp with no invasion of stalk

Clark level 1 for melanoma (limited to epithelium)

Comedocarcinoma, noninfiltrating (C50._)

2

Synonymous with in situ

Behavior code ‘2’

Bowen disease (not reportable for C440-C449)

Clark level I for melanoma (limited to epithelium)

Confined to epithelium

Hutchinson melanotic freckle, NOS (C44_)

Intracystic, noninfiltrating (carcinoma)

Intraductal (carcinoma)

Intraepidermal, NOS (carcinoma)

Intraepithelial neoplasia, Grade III (e.g., AIN III, LIN III, SIN III, VAIN III, VIN III)

Intraepithelial, NOS (carcinoma)

Involvement up to, but not including the basement membrane

Lentigo maligna (C44._)

Lobular, noninfiltrating (C50._) (carcinoma)

Noninfiltrating (carcinoma)

Non-invasive (carcinoma)

No stromal invasion/involvement

Papillary, noninfiltrating, or intraductal (carcinoma)

Precancerous melanosis (C44._)

Stage 0 (except Paget’s disease (8540/3) of breast and colon or rectal tumors confined to the lamina propria)

3

Invasive

Malignant



Primary site Invasive



Microinvasive



Focus of invasion

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